1. Neural correlates:
The neural correlates of social connection: an fMRI study of the perception of social closeness (Morelli SA, Rameson LT, Lieberman MD., 2014). Social Cognitive and Affective Neuroscience.
Abstract: An fMRI study showing that perception of social proximity (proximity to friends, family) is associated with activation of brain regions associated with social cognition (mPFC, TPJ) and the reward system (VTA, striatum).
Keywords: social connection, social closeness, fMRI, mPFC, TPJ, VTA, striatum, reward system.
Friends vs. Strangers: An fMRI Study of Social Proximity (Fareri, D. S., & Delgado, M. R., 2014). Social Cognitive and Affective Neuroscience.
Abstract: An fMRI study examined the difference in neural responses to interactions with friends and strangers.
Keywords: fMRI, friends, strangers, social proximity, reward system, trust.
Friendship and the Banker: An fMRI Study of Trust Development in Social Exchange (King-Casas B, et al., 2005). Science.
Abstract: Studying the dynamics of trust.
Keywords: fMRI, trust, social exchange, insula, caudate nucleus.
2. Neurochemical patterns:
The neurochemistry of social bonding, social dysfunction, and therapeutic approaches to enhancing social behavior (Insel TR., 2010). CNS Spectrums.
Review: A review article examining the role of oxytocin and vasopressin in social behavior, including the formation of friendships and social attachment. The potential of therapeutic use of oxytocin for improving social interaction is discussed.
Keywords: oxytocin, vasopressin, social bonding, social behavior, autism, social anxiety disorder.
Social Interaction Reward: A Common Neurobiological Substrate (Trezza V, Baarendse PJ, Vanderschuren LJ., 2010)
Review: Literature review.
Keywords: Social Interaction, reward, dopamine, opioids, oxytocin
Oxytocin and the social salience hypothesis (Shamay-Tsoory SG, Abu-Akel A., 2016). Current Opinion in Behavioral Sciences.
Abstract: We discuss the hypothesis that oxytocin enhances the perception of social signals, making them more meaningful, which may contribute to both prosocial and antisocial behavior, depending on the context.
Key words: oxytocin, social salience, social cognition, prosocial behavior, antisocial behavior.
3. Hormonal Patterns:
Oxytocin, vasopressin, and the neurogenetics of sociality (Donaldson ZR, Young LJ., 2008). Science.
Review: A review article examining the role of oxytocin and vasopressin, as well as genetic factors, in regulating social behavior in various animal species, including humans.
Keywords: oxytocin, vasopressin, social behavior, genetics, pair bonding, social recognition.
Salivary testosterone and cortisol in preschool children: Relationships to social behavior and peer problems (Ahnert L, Gunnar MR, Lamb ME, Barthel M., 2004). Child Development.
Abstract: The effect of hormones.
Keywords: testosterone, cortisol, social behavior, peer problems, preschool children.
Social support and the human stress response (Heinrichs M, Baumgartner T, Kirschbaum C, Ehlert U., 2003). Biological Psychiatry.
Abstract: A study showing that social support (having friends) can reduce the level of cortisol (the stress hormone) in stressful situations.
Keywords: social support, stress, cortisol, HPA axis.
4. Biological patterns:
Social buffering: relief from stress and anxiety (Kiyokawa Y, Takeuchi Y, Mori Y., 2014). Philosophical Transactions of the Royal Society B: Biological Sciences.
Review: A review article that examines the phenomenon of "social buffer", when the presence of social partners (friends, relatives) reduces stress and anxiety.
Keywords: social buffering, stress, anxiety, social support, allostasis.
The evolutionary significance of friendship (Dunbar RIM., 2018). Evolutionary Psychology.
Overview: The evolutionary significance of friendship.
Keywords: Friendship, evolution, cooperation, social brain
Friendship and well-being across the life span (Blieszner, R., & Roberto, K. A., 2012).
Abstract: A review of the literature showing the impact of friendship on well-being in the course of life.
Keywords: friendship, well-being, life span, social support, loneliness.
5. Social Implications:
The health benefits of strong social relationships (Holt-Lunstad J, Smith TB, Layton JB., 2010). PLoS Medicine.
Review: A meta-analysis of studies showing that having strong social connections (including friendships) is associated with improved health and reduced risk of mortality.
Keywords: social relationships, social support, health, mortality, loneliness.
Friendship quality and social development (Hartup WW., 1996). Current Directions in Psychological Science.
Abstract: The influence of friendship quality on social development.
Keywords: friendship, quality, social development, children, adolescents
Loneliness as a specific risk factor for depressive symptoms: cross-sectional and longitudinal analyses (Cacioppo JT, Hughes ME, Waite LJ, Hawkley LC, Thisted RA., 2006). Psychology and Aging.
Abstract: A study showing that loneliness (lack of close friends) is a specific risk factor for the development of depressive symptoms.
Keywords: loneliness, social isolation, depression, mental health, longitudinal study.
Social capital: Its origins and applications in modern sociology (Portes A., 1998). Annual review of sociology.
Abstract: Literature review.
Keywords: Social capital, networks, trust, norms, sociology
6. Clinical implications of Phylia:
Social anxiety disorder: recognition, assessment and treatment (National Institute for Health and Care Excellence (NICE), 2013). Clinical guideline [CG159].
Guidelines: Clinical guidelines for the diagnosis, assessment, and treatment of social anxiety disorder (social phobia), which is characterized by fear of social situations and difficulties in establishing social contacts, including friendships.
Keywords: social anxiety disorder, social phobia, anxiety, treatment, CBT, psychotherapy.
Autism spectrum disorder in adults: diagnosis and management (National Institute for Health and Care Excellence (NICE), 2012). Clinical guideline [CG142].
Guidelines: Clinical guidelines for the diagnosis and management of autism spectrum disorders (ASD) in adults, with a focus on difficulties in social interaction and forming relationships, including friendships.
Keywords: autism spectrum disorder, ASD, social interaction, social communication, diagnosis, management.
Loneliness Matters: A Theoretical and Empirical Review of Consequences and Mechanisms (Hawkley, L. C., & Cacioppo, J. T., 2010). Annals of Behavioral Medicine.
Overview: A review article on the effects and mechanisms of loneliness, with a focus on its impact on mental and physical health.
Keywords: loneliness, social isolation, health, mental health, mechanisms.